BDBM50019245 1H-Pyrrole-2-carboxylic acid [5-(2-fluoro-phenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-amide::1H-Pyrrole-2-carboxylic acid [5-(2-fluoro-phenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-amide: 0.25C4H8O::CHEMBL73272

SMILES Fc1ccccc1C1=NC(NC(=O)c2ccc[nH]2)C(=O)Nc2ccccc12

InChI Key InChIKey=MQRCNHWIJBHISY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50019245   

TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019245(1H-Pyrrole-2-carboxylic acid [5-(2-fluoro-phenyl)-...)
Affinity DataIC50:  2.50E+4nMAssay Description:Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glandsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019245(1H-Pyrrole-2-carboxylic acid [5-(2-fluoro-phenyl)-...)
Affinity DataIC50:  1.00E+5nMAssay Description:Half-maximal inhibition of [125I]-CCK-8(+) binding to cholecystokinin receptor from guinea pig brain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50019245(1H-Pyrrole-2-carboxylic acid [5-(2-fluoro-phenyl)-...)
Affinity DataIC50:  110nMAssay Description:Binding affinity against cholecystokinin type A receptor of rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50019245(1H-Pyrrole-2-carboxylic acid [5-(2-fluoro-phenyl)-...)
Affinity DataIC50:  110nMAssay Description:Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed