BDBM50020044 CHEMBL3287898

SMILES CCc1ccccc1NC(=O)N1C[C@@H](C)Oc2cc(ccc12)-c1ccc(cc1)[C@H]1CC[C@H](CC(O)=O)CC1

InChI Key InChIKey=PUQLADUSPHHAJY-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50020044   

TargetDiacylglycerol O-acyltransferase 1(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020044(CHEMBL3287898)
Affinity DataIC50: 44nMAssay Description:Inhibition of mouse DGAT1 expressed in Sf9 insect cells using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA substrate by scintillation counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020044(CHEMBL3287898)
Affinity DataIC50: 64nMAssay Description:Inhibition of human DGAT1 expressed in Sf9 insect cells using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA substrate by scintillation counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020044(CHEMBL3287898)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of prostanoid IP receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetCaspase-9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020044(CHEMBL3287898)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CASP9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020044(CHEMBL3287898)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of insulin receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetCaspase-8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020044(CHEMBL3287898)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of CASP8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020044(CHEMBL3287898)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of EGF receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020044(CHEMBL3287898)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of D2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020044(CHEMBL3287898)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CB1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed