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BDBM50020512 6-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylamine::CHEMBL99215

SMILES: COc1ccc2CC(N)CCc2c1

InChI Key: InChIKey=WASIYUSITZITPW-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50020512   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phenylethanolamine N-methyltransferase


(Bos taurus (bovine))
BDBM50020512
PNG
(6-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylamine ...)
Show SMILES COc1ccc2CC(N)CCc2c1
Show InChI InChI=1S/C11H15NO/c1-13-11-5-3-8-6-10(12)4-2-9(8)7-11/h3,5,7,10H,2,4,6,12H2,1H3
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
3.40E+4n/an/an/an/an/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against bovine phenylethanolamine N-methyl-transferase


J Med Chem 32: 478-86 (1989)


Article DOI: 10.1021/jm00122a032
BindingDB Entry DOI: 10.7270/Q2P55P32
More data for this
Ligand-Target Pair
Melatonin receptor


(Gallus gallus-Chick)
BDBM50020512
PNG
(6-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylamine ...)
Show SMILES COc1ccc2CC(N)CCc2c1
Show InChI InChI=1S/C11H15NO/c1-13-11-5-3-8-6-10(12)4-2-9(8)7-11/h3,5,7,10H,2,4,6,12H2,1H3
UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
>1.00E+5n/an/an/an/an/an/an/an/a



University of Groningen

Curated by ChEMBL


Assay Description
Binding affinity to compete for 2-[125I]iodomelatonin binding to chicken retinal membranes


J Med Chem 36: 2891-8 (1993)

More data for this
Ligand-Target Pair