BDBM50020912 Largazole Thiol

SMILES: [H][C@]1(CC(=O)NCc2nc(cs2)C2=N[C@@](C)(CS2)C(=O)N[C@H](C(C)C)C(=O)O1)\C=C\CCS

InChI Key: InChIKey=VEDPEVJAYWVUSJ-UHFFFAOYSA-N

Data: 14 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50020912   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 3 (Human)	BDBM50020912 (Largazole Thiol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 6 (Human)	BDBM50020912 (Largazole Thiol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 1 (Human)	BDBM50020912 (Largazole Thiol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 2 (Human)	BDBM50020912 (Largazole Thiol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 1 (Human)	BDBM50020912 (Largazole Thiol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 3 (Human)	BDBM50020912 (Largazole Thiol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 8 (Human)	BDBM50020912 (Largazole Thiol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 1 (Human)	BDBM50020912 (Largazole Thiol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 2 (Human)	BDBM50020912 (Largazole Thiol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 3 (Human)	BDBM50020912 (Largazole Thiol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 6 (Human)	BDBM50020912 (Largazole Thiol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 8 (Human)	BDBM50020912 (Largazole Thiol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
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Polyamine deacetylase HDAC10 (Human)	BDBM50020912 (Largazole Thiol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 11 (Human)	BDBM50020912 (Largazole Thiol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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