BDBM50024204 1H-imidazo[4,5-c]pyridine derivative::2N-[4,7-dimethyl-(6aR,9S,10aR)-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl]-2-dimethylaminosulfonamide::4,7-dimethyl-(6aR,9S,10aR)-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-amino-N,N-dimethyl sulfonamide::4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-amine-sulfonamide::9-N,N-dimethylsulfamide-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::CHEMBL12314::ChEMBL_10959::MESULERGINE::N'-4,7-Dimethyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-yl)-N'-,N'-dimethyl-sulphonediamine

SMILES: CN(C)S(=O)(=O)N[C@H]1C[C@H]2[C@@H](Cc3cn(C)c4cccc2c34)N(C)C1

InChI Key: InChIKey=JLVHTNZNKOSCNB-UHFFFAOYSA-N

Data: 86 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 88 hits for monomerid = 50024204   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Human)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Pig)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		3.01	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		3.01	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		3.62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		6.31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		7.07	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		7.13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Human)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		7.94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Bovine)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		9.33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Human)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		12.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Guinea pig)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		12.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Human)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		13.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Guinea pig)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		15.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Guinea pig)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		15.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		15.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Human)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Human)	BDBM50024204 (MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...) Show SMILES Show InChI	GoogleScholar	UniChem		18.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair