BDBM50026868 2-(1H-indol-3-yl)-N,N-dimethylethanamine::2-(3-indolyl)ethyldimethylamine::3-(2-dimethylaminoethyl)indole::3-[2-(dimethylamino)ethyl]indole::CHEMBL12420::DMT::N,N-dimethyl-1H-indole-3-ethylamine::N,N-dimethyltryptamine::US20240166618, Compound DMT::US20240246911, Compound DMT::US20240317683, Compound DMT::WO2023019367, Compound DMT

SMILES: CN(C)CCc1c[nH]c2c1cccc2

InChI Key: InChIKey=DMULVCHRPCFFGV-UHFFFAOYSA-N

Data: 44 KI  36 IC50  1 Kd  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 132 hits for monomerid = 50026868   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a
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Sodium-dependent serotonin transporter (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	181	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	440	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	28.9	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 5A (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 5A (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1D adrenergic receptor (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Amine oxidase [flavin-containing] A (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Amine oxidase [flavin-containing] A (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2B (Rat)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50026868 (2-(1H-indol-3-yl)-N,N-dimethylethanamine | DMT | N...) Show SMILES Show InChI	GoogleScholar	UniChem		60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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