BDBM50026884 CHEMBL405282

SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(O)=O

InChI Key InChIKey=GZWUQPQBOGLSIM-MDMVXOTPSA-N

Data  3 IC50  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50026884   

TargetMelanocortin receptor 5(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50026884(CHEMBL405282)
Affinity DataIC50:  340nMAssay Description:Binding affinity for Human Melanocortin 5 receptor expressed in L-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50026884(CHEMBL405282)
Affinity DataEC50:  82nMAssay Description:Effective concentration required for intracellular cAMP accumulation by Melanocortin 5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50026884(CHEMBL405282)
Affinity DataIC50:  6.70nMAssay Description:Binding affinity for Human Melanocortin 3 receptor expressed in L-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50026884(CHEMBL405282)
Affinity DataEC50:  0.330nMAssay Description:Effective concentration required for intracellular cAMP accumulation against Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Mus musculus (Mouse))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50026884(CHEMBL405282)
Affinity DataEC50:  35nMAssay Description:Agonist activity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50026884(CHEMBL405282)
Affinity DataEC50:  100nMAssay Description:Effective concentration required for intracellular cAMP accumulation by Melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50026884(CHEMBL405282)
Affinity DataEC50:  1.09E+3nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50026884(CHEMBL405282)
Affinity DataEC50:  35nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mus musculus)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50026884(CHEMBL405282)
Affinity DataEC50:  869nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50026884(CHEMBL405282)
Affinity DataIC50:  600nMAssay Description:Binding affinity for Human Melanocortin 4 receptor expressed in L-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed