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BDBM50027475 (E)-1-(2,4-dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-propen-1-one (3)::2,2'',4''-Trihydroxychalcone::CHEMBL148472

SMILES: Oc1ccc(C(=O)\C=C\c2ccccc2O)c(O)c1

InChI Key: InChIKey=MACMAADVRVVHBD-UHFFFAOYSA-N

Data: 5 IC50 1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50027475
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Beta-secretase 1 (Human)	BDBM50027475 (2,2'',4''-Trihydroxychalcone \| CHEMBL148472 \| (E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a	4.5	37
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bovine)	BDBM50027475 (2,2'',4''-Trihydroxychalcone \| CHEMBL148472 \| (E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus type 1)	BDBM50027475 (2,2'',4''-Trihydroxychalcone \| CHEMBL148472 \| (E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus type 1)	BDBM50027475 (2,2'',4''-Trihydroxychalcone \| CHEMBL148472 \| (E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rat)	BDBM50027475 (2,2'',4''-Trihydroxychalcone \| CHEMBL148472 \| (E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50027475 (2,2'',4''-Trihydroxychalcone \| CHEMBL148472 \| (E)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair