BDBM50031795 (N-(2-HYDROXAMATEMETHYLENE-4-METHYL-PENTOYL)PHENYLALANYL)METHYL AMINE::(R)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methylcarbamoyl-2-phenyl-ethyl)-succinamide::(R)-N4-hydroxy-2-isobutyl-N1-((S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl)succinamide::CHEMBL11306::METHYLAMINO-PHENYLALANYL-LEUCYL-HYDROXAMIC ACID
SMILES CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)CC(=O)NO
InChI Key InChIKey=MOPRTFSMCQNUCT-CABCVRRESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 24 hits for monomerid = 50031795
Affinity DataKi: <1nMAssay Description:Inhibition of human Matrix metalloproteinase-8More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of human Matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of human neutrophil collagenase(HNC), MMP-8More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibitory concentration of compound against human fibroblast stromelysin (HFS) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloproteinase-1More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloproteinase-1More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibitory potency against human fibroblast collagenase, MMP-1More data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Inhibitory potency against human stromelysin, MMP-3More data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Inhibitory concentration of compound against human neutrophil collagenase (HNC) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloproteinase-3More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity to dihydrofolate reductase in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0460nMAssay Description:Inhibition of human recombinant MMP8More data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibition of human recombinant MMP7More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant MMP3More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against Dihydrofolate reductase in Neisseria gonorrhoeaeMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Cathepsin L from human kidneyMore data for this Ligand-Target Pair
Affinity DataIC50: 0.380nMAssay Description:Inhibition of human recombinant MMP9More data for this Ligand-Target Pair
TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 1000...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant MMP2More data for this Ligand-Target Pair