BindingDB logo
myBDB logout

BDBM50033003 (3-Amino-propyl)-diethoxymethyl-phosphinic acid::CGP-35348::CHEMBL40157

SMILES: CCOC(OCC)P(O)(=O)CCCN

InChI Key: InChIKey=QIIVUOWTHWIXFO-UHFFFAOYSA-N

Data: 2 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50033003   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GABA-B receptor 1/2


(Rattus norvegicus (Rat))
BDBM50033003
PNG
((3-Amino-propyl)-diethoxymethyl-phosphinic acid | ...)
Show SMILES CCOC(OCC)P(O)(=O)CCCN
Show InChI InChI=1S/C8H20NO4P/c1-3-12-8(13-4-2)14(10,11)7-5-6-9/h8H,3-7,9H2,1-2H3,(H,10,11)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
n/an/a 2.50E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro displacement of [3H]-GABA from Gamma-aminobutyric acid type B receptor sites in rat brain membranes


Bioorg Med Chem Lett 3: 515-518 (1993)


Article DOI: 10.1016/S0960-894X(01)81218-X
BindingDB Entry DOI: 10.7270/Q2BR8S4N
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1


(Rattus norvegicus (Rat))
BDBM50033003
PNG
((3-Amino-propyl)-diethoxymethyl-phosphinic acid | ...)
Show SMILES CCOC(OCC)P(O)(=O)CCCN
Show InChI InChI=1S/C8H20NO4P/c1-3-12-8(13-4-2)14(10,11)7-5-6-9/h8H,3-7,9H2,1-2H3,(H,10,11)
PDB

Reactome pathway

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
PubMed
n/an/a 2.70E+4n/an/an/an/an/an/a



Ciba-Geigy AG

Curated by ChEMBL


Assay Description
Inhibition of binding of [3H]-CGP-27,492 to gamma-aminobutyric acid type B receptor of rat cortex.


J Med Chem 38: 3313-31 (1995)


Article DOI: 10.1021/jm00017a016
BindingDB Entry DOI: 10.7270/Q2HD7TPZ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)