BDBM50033327 (2-Phenyl-quinazolin-4-yl)-pyridin-3-ylmethyl-amine::CHEMBL420539::cid_675226

SMILES C(Nc1nc(nc2ccccc12)-c1ccccc1)c1cccnc1

InChI Key InChIKey=NWGXQMVEYOMULC-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50033327   

TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50033327(CHEMBL420539 | cid_675226 | (2-Phenyl-quinazolin-4...)
Affinity DataIC50: 8.37E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
LigandPNGBDBM50033327(CHEMBL420539 | cid_675226 | (2-Phenyl-quinazolin-4...)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibitory activity against phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50033327(CHEMBL420539 | cid_675226 | (2-Phenyl-quinazolin-4...)
Affinity DataIC50: 2.51E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50033327(CHEMBL420539 | cid_675226 | (2-Phenyl-quinazolin-4...)
Affinity DataIC50: 8.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50033327(CHEMBL420539 | cid_675226 | (2-Phenyl-quinazolin-4...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay