BDBM50034465 CHEMBL30199::N-[5-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-naphthalen-1-yl]-acetamide
SMILES CC(=O)Nc1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C
InChI Key InChIKey=RUCGYYIEJGBLLO-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50034465
TargetEndothelin-1 receptor(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 880nMAssay Description:Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells.More data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 880nMAssay Description:Ability to inhibit [125I]-ET1 binding to vascular smooth muscle (vsm)- A10 cellsMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibition of [125I]-endothelin-l binding to endothelin A receptor of rat thoracic aorta smooth muscle cellsMore data for this Ligand-Target Pair