BDBM50036737 (R)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::CHEMBL129768

SMILES: O[C@H](CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1

InChI Key: InChIKey=ZXUYYZPJUGQHLQ-UHFFFAOYSA-N

Data: 3 KI  7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50036737   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Human)	BDBM50036737 ((R)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50036737 ((R)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
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Sigma non-opioid intracellular receptor 1 (Human)	BDBM50036737 ((R)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
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Sigma non-opioid intracellular receptor 1 (Human)	BDBM50036737 ((R)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Rat)	BDBM50036737 ((R)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50036737 ((R)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Human)	BDBM50036737 ((R)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	437	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Human)	BDBM50036737 ((R)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2...) Show SMILES Show InChI	GoogleScholar	UniChem		64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50036737 ((R)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50036737 ((R)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair