BDBM50039061 6,7-Dimethoxy-3-(5-methoxy-thiophen-2-yl)-quinoline::CHEMBL302745

SMILES COc1ccc(s1)-c1cnc2cc(OC)c(OC)cc2c1

InChI Key InChIKey=JIQNEEKYQFLLCR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50039061   

TargetPlatelet-derived growth factor receptor alpha/beta(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50039061(6,7-Dimethoxy-3-(5-methoxy-thiophen-2-yl)-quinolin...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.1-0.25More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50039061(6,7-Dimethoxy-3-(5-methoxy-thiophen-2-yl)-quinolin...)
Affinity DataIC50: 2.00E+4nMAssay Description:Concentration required to inhibit phosphorylation of isolated human epidermal growth factor tyrosine kinase receptor by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed