BDBM50040344 8-Amino-1,3-bis-cyclopropylmethyl-7-(propane-2-sulfonyl)-3,7-dihydro-purine-2,6-dione::CHEMBL439809

SMILES CC(C)S(=O)(=O)n1c(N)nc2n(CC3CC3)c(=O)n(CC3CC3)c(=O)c12

InChI Key InChIKey=MYLOBMKMTNGKLK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50040344   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040344(8-Amino-1,3-bis-cyclopropylmethyl-7-(propane-2-sul...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of adenosine binding to A1 receptorof rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50040344(8-Amino-1,3-bis-cyclopropylmethyl-7-(propane-2-sul...)
Affinity DataIC50:  3.80E+4nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 microM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed