BDBM50041187 CHEMBL3355946

SMILES CCc1[nH]c2cc(O)ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1

InChI Key InChIKey=RUBACXIFRPVRKI-UHFFFAOYSA-N

Data  3 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50041187   

TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Boehringer Ingelheim Pharma GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50041187(CHEMBL3355946)
Show SMILES CCc1[nH]c2cc(O)ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1
Show InChI InChI=1S/C24H29FN2OS/c1-2-22-24(21-9-6-19(28)16-23(21)26-22)17-10-13-27(14-11-17)12-3-15-29-20-7-4-18(25)5-8-20/h4-9,16-17,26,28H,2-3,10-15H2,1H3
Affinity DataKi:  86nMAssay Description:Displacement of [125J]-eotaxin-1 from human CCR3 transfected in human K562 cellsMore data for this Ligand-Target Pair
TargetProbable C-C chemokine receptor type 3(Mus musculus)
Boehringer Ingelheim Pharma GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50041187(CHEMBL3355946)
Show SMILES CCc1[nH]c2cc(O)ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1
Show InChI InChI=1S/C24H29FN2OS/c1-2-22-24(21-9-6-19(28)16-23(21)26-22)17-10-13-27(14-11-17)12-3-15-29-20-7-4-18(25)5-8-20/h4-9,16-17,26,28H,2-3,10-15H2,1H3
Affinity DataKi:  370nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Rattus norvegicus)
Boehringer Ingelheim Pharma GmbH & Co. KG

Curated by ChEMBL
LigandPNGBDBM50041187(CHEMBL3355946)
Show SMILES CCc1[nH]c2cc(O)ccc2c1C1CCN(CCCSc2ccc(F)cc2)CC1
Show InChI InChI=1S/C24H29FN2OS/c1-2-22-24(21-9-6-19(28)16-23(21)26-22)17-10-13-27(14-11-17)12-3-15-29-20-7-4-18(25)5-8-20/h4-9,16-17,26,28H,2-3,10-15H2,1H3
Affinity DataKi:  560nMAssay Description:Displacement of [125J]-eotaxin-1 from rat CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair