BDBM50043353 1,8-Dihydroxy-10-(3,4,5-trihydroxy-benzylidene)-10H-anthracen-9-one::CHEMBL133805

SMILES [#8]-c1cc(\[#6]=[#6]-2\c3cccc(-[#8])c3-[#6](=O)-c3c(-[#8])cccc-23)cc(-[#8])c1-[#8]

InChI Key InChIKey=MCYXTPNILAVSKG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043353   

Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50043353(1,8-Dihydroxy-10-(3,4,5-trihydroxy-benzylidene)-10...)
Affinity DataIC50:  2.00E+3nMAssay Description:Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
UniversitäT Regensburg

Curated by ChEMBL
LigandPNGBDBM50043353(1,8-Dihydroxy-10-(3,4,5-trihydroxy-benzylidene)-10...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed