BDBM50044161 CHEMBL3314022

SMILES CC(C)C(C)N(c1ccc(cn1)C(C)C)S(=O)(=O)c1ccc(OCC2CCOCC2)cc1

InChI Key InChIKey=MHVBWCHVZNJXOJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044161   

TargetNuclear receptor ROR-gamma(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50044161(CHEMBL3314022)
Affinity DataEC50: <32nMAssay Description:Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50044161(CHEMBL3314022)
Affinity DataEC50: <1.00E+3nMAssay Description:Agonist activity at human RoRc-LBD in human PBMC cells assessed as inhibition of IL-17A production by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed