BDBM50044649 CHEMBL3309290

SMILES CC1(C)CC(=O)Nc2ccc(cc12)C(=O)NCc1cccc(\C=C\C(=O)NO)c1

InChI Key InChIKey=ROVKUEFHZPOYAM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50044649   

TargetHistone deacetylase 2(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50044649BDBM50044649(CHEMBL3309290)
Affinity DataIC50: 100nMAssay Description:Inhibition of human HDAC2 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50044649BDBM50044649(CHEMBL3309290)
Affinity DataIC50: 200nMAssay Description:Inhibition of human HDAC8 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50044649BDBM50044649(CHEMBL3309290)
Affinity DataIC50: 210nMAssay Description:Inhibition of human HDAC3 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50044649BDBM50044649(CHEMBL3309290)
Affinity DataIC50: 290nMAssay Description:Inhibition of human HDAC6 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50044649BDBM50044649(CHEMBL3309290)
Affinity DataIC50: 570nMAssay Description:Inhibition of human HDAC9 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50044649BDBM50044649(CHEMBL3309290)
Affinity DataIC50: 670nMAssay Description:Inhibition of human HDAC1 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Nippon Pharmaceutical Chemicals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50044649BDBM50044649(CHEMBL3309290)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human HDAC4 pre-incubated for 30 mins before substrate addition and measured after 30 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed