BDBM50045114 3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::CHEMBL55033::EKC

SMILES CCC12CCN(CC3CC3)C(C1C)C(=O)c1ccc(O)cc21

InChI Key InChIKey=SEJUQQOPVAUETF-UHFFFAOYSA-N

Data  13 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50045114   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  0.620nMAssay Description:Displacement of [3H]U69593 form kappa opioid receptor in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  0.620nMAssay Description:Displacement of [3H]U69,593 from KOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  0.620nMAssay Description:Binding affinity to KOR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  0.780nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  0.780nMAssay Description:Displacement of [3H]DAMGO form mu opioid receptor in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity to MOR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by PDSP Ki Database
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  1.93nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by PDSP Ki Database
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  2.12nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by PDSP Ki Database
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  2.46nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOpioid receptor delta 1(Cavia porcellus)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]Naltrindole from DOR in guinea pig brain membranes after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity to DOR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  188nMAssay Description:Binding affinity for kappa opioid receptor was evaluated by displacing [3H]- diprenorphineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by PDSP Ki Database
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  690nMAssay Description:Binding affinity for mu opioid receptor was evaluated by displacing [3H]- diprenorphineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed