BDBM50045740 3-[3,4-Dimethyl-1-(2-p-tolyl-ethyl)-piperidin-4-yl]-phenol::CHEMBL98407

SMILES C[C@H]1CN(CCc2ccc(C)cc2)CC[C@@]1(C)c1cccc(O)c1

InChI Key InChIKey=NWVPKBPQGPPLNG-PGRDOPGGSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50045740   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045740(3-[3,4-Dimethyl-1-(2-p-tolyl-ethyl)-piperidin-4-yl...)
Affinity DataKi:  13nMAssay Description:Binding affinity towards mu opioid receptor by displacement of [3H]-NAL from rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045740(3-[3,4-Dimethyl-1-(2-p-tolyl-ethyl)-piperidin-4-yl...)
Affinity DataKi:  52nMAssay Description:Binding affinity towards mu-opioid receptor by displacement of [3H]-NAL at 10 nM from rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045740(3-[3,4-Dimethyl-1-(2-p-tolyl-ethyl)-piperidin-4-yl...)
Affinity DataKi:  61nMAssay Description:Binding affinity towards kappa-opioid receptor by displacement of [3H]-EKC at 100 nM from guinea pig cortical tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045740(3-[3,4-Dimethyl-1-(2-p-tolyl-ethyl)-piperidin-4-yl...)
Affinity DataKi:  95nMAssay Description:Binding affinity towards mu-opioid receptor by displacement of [3H]NAL at 100 nM from rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed