BDBM50046258 3-(4-Hydroxy-phenyl)-2-[2-(3-mercapto-5-methyl-hexanoylamino)-3-phenyl-propionylamino]-propionic acid::3-(4-hydroxyphenyl)-2-(2-(3-mercapto-5-methylhexanamido)-3-phenylpropanamido)propanoic acid::CHEMBL367174

SMILES CC(C)CC(S)CC(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(O)=O

InChI Key InChIKey=YEXFSKCFFQBJBR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50046258   

TargetNeprilysin(Oryctolagus cuniculus (rabbit))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50046258(3-(4-Hydroxy-phenyl)-2-[2-(3-mercapto-5-methyl-hex...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration was evaluated by Inhibiting 50% of Neutral endopeptidase enzyme (NEP) activity using 20 nM [3H]-D-Ala2-Leu-enkephalin as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50046258(3-(4-Hydroxy-phenyl)-2-[2-(3-mercapto-5-methyl-hex...)
Affinity DataIC50:  50nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50046258(3-(4-Hydroxy-phenyl)-2-[2-(3-mercapto-5-methyl-hex...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50046258(3-(4-Hydroxy-phenyl)-2-[2-(3-mercapto-5-methyl-hex...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibitory concentration was evaluated by Inhibiting 50% of Angiotensin I converting enzyme activity using 50 microM N-Cbz-Phe-His-Leu as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed