BDBM50049506 5-Bromo-2-((1S,3R)-3-bromo-2,2-dimethyl-6-methylene-cyclohexylmethyl)-4-methoxy-phenol::CHEMBL51093

SMILES COc1cc(C[C@H]2C(=C)CC[C@@H](Br)C2(C)C)c(O)cc1Br

InChI Key InChIKey=UHRXKJFPPKYYEC-BLLLJJGKSA-N

Data  3 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50049506   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049506(5-Bromo-2-((1S,3R)-3-bromo-2,2-dimethyl-6-methylen...)
Affinity DataKi:  490nMAssay Description:Binding affinity determined for human Progesterone receptor A isoformMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50049506(5-Bromo-2-((1S,3R)-3-bromo-2,2-dimethyl-6-methylen...)
Affinity DataKi:  2.47E+3nMAssay Description:Displacement of [3H]DEX from human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50049506(5-Bromo-2-((1S,3R)-3-bromo-2,2-dimethyl-6-methylen...)
Affinity DataKi:  3.21E+3nMAssay Description:Binding affinity against human glucocorticoid receptor(hGR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049506(5-Bromo-2-((1S,3R)-3-bromo-2,2-dimethyl-6-methylen...)
Affinity DataIC50:  449nMAssay Description:Inhibitory activity against human Androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049506(5-Bromo-2-((1S,3R)-3-bromo-2,2-dimethyl-6-methylen...)
Affinity DataIC50:  549nMAssay Description:Concentration required to give half-maximal inhibition against human Progesterone receptor B isoform in co-transfected CV-1 cell lines.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049506(5-Bromo-2-((1S,3R)-3-bromo-2,2-dimethyl-6-methylen...)
Affinity DataIC50:  354nMAssay Description:Antagonistic potency to the human progesterone receptor measured in the T-47D alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50049506(5-Bromo-2-((1S,3R)-3-bromo-2,2-dimethyl-6-methylen...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against human glucocorticoid receptor (hGR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed