BDBM50051842 CHEBI:83682::Demofix::Ertaczo::Sertaconazole

SMILES Clc1ccc(C(Cn2ccnc2)OCc2csc3c(Cl)cccc23)c(Cl)c1

InChI Key InChIKey=JLGKQTAYUIMGRK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50051842   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Swiss Institute Of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50051842(CHEBI:83682 | Demofix | Ertaczo | Sertaconazole)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of IDO1 (unknown origin) using L-tryptophan substrate incubated for 60 mins by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Swiss Institute Of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50051842(CHEBI:83682 | Demofix | Ertaczo | Sertaconazole)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human N-terminal IDO1 expressed in Escherichia coli BL21 A1 cells using L-tryptophan as substrate measured after 30 mins by HPLC analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Southwest University

Curated by ChEMBL
LigandPNGBDBM50051842(CHEBI:83682 | Demofix | Ertaczo | Sertaconazole)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed