BDBM50053551 4-(4-Fluoro-phenyl)-7-[3-(4-hydroxy-tetrahydro-pyran-4-yl)-benzyloxy]-3H-naphtho[2,3-c]furan-1-one::CHEMBL414375

SMILES OC1(CCOCC1)c1cccc(COc2ccc3c(c4COC(=O)c4cc3c2)-c2ccc(F)cc2)c1

InChI Key InChIKey=ODQXHWBQMAEXIT-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50053551   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50053551(4-(4-Fluoro-phenyl)-7-[3-(4-hydroxy-tetrahydro-pyr...)
Show SMILES OC1(CCOCC1)c1cccc(COc2ccc3c(c4COC(=O)c4cc3c2)-c2ccc(F)cc2)c1
Show InChI InChI=1S/C30H25FO5/c31-23-6-4-20(5-7-23)28-25-9-8-24(15-21(25)16-26-27(28)18-36-29(26)32)35-17-19-2-1-3-22(14-19)30(33)10-12-34-13-11-30/h1-9,14-16,33H,10-13,17-18H2
Affinity DataIC50: 140nMAssay Description:Potency to inhibit oxidation of arachidonic acid by recombinant human 5-lipoxygenaseMore data for this Ligand-Target Pair