BDBM50057607 4-[5-(3,4-Dimethoxy-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide::CHEMBL282360
SMILES COc1ccc(cc1OC)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F
InChI Key InChIKey=VNNGIYNQDQOQCJ-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50057607
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 603nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 603nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair