BDBM50057787 CHEMBL3322999::US9598387, Compound 130::US9969743, 130

SMILES FC(F)(F)c1cc(N2CCN(CCCCNC(=O)c3cn4ccccc4n3)CC2)c2ccccc2n1

InChI Key InChIKey=SJNLUIGGLBDGFM-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50057787   

TargetD(3) dopamine receptor(Human)
Southern Research Institute

US Patent
LigandPNGBDBM50057787(CHEMBL3322999 | US9598387, Compound 130 | US996974...)
Affinity DataKi:  524nMAssay Description:Stably transfected HEK cells expressing the human D2-long and the D3 dopamine receptor were developed using the pIRESneo2 bicistronic expression vect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
Southern Research Institute

US Patent
LigandPNGBDBM50057787(CHEMBL3322999 | US9598387, Compound 130 | US996974...)
Affinity DataKi:  524nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
Southern Research Institute

US Patent
LigandPNGBDBM50057787(CHEMBL3322999 | US9598387, Compound 130 | US996974...)
Affinity DataKi:  524nMAssay Description:Displacement of [125I]IABN from human D3R expressed in HEK293 cell membranes by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

US Patent
LigandPNGBDBM50057787(CHEMBL3322999 | US9598387, Compound 130 | US996974...)
Affinity DataKi:  1.36E+4nMAssay Description:Stably transfected HEK cells expressing the human D2-long and the D3 dopamine receptor were developed using the pIRESneo2 bicistronic expression vect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Southern Research Institute

US Patent
LigandPNGBDBM50057787(CHEMBL3322999 | US9598387, Compound 130 | US996974...)
Affinity DataKi:  1.36E+4nMAssay Description:Displacement of [125I]IABN from human D2LR expressed in HEK293 cell membranes by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Southern Research Institute

US Patent
LigandPNGBDBM50057787(CHEMBL3322999 | US9598387, Compound 130 | US996974...)
Affinity DataKi:  1.36E+4nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent