BDBM50059523 (6Z,9Z,12Z,15Z)-1,1,1-trifluorohenicosa-6,9,12,15-tetraen-2-one::AACOCF3::Arachidonic acid trifluoromethyl ketone::Arachidonyl trifluoromethyl ketone::Arachidonyltrifluoromethane::CHEMBL281211
SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)C(F)(F)F
InChI Key InChIKey=PLWROONZUDKYKG-DOFZRALJSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50059523
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity against cPLA2 (cytosolic Phospholipase A2) by measuring the calcium ionophore A-23,187-induced arachidonic acid release from bovi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of cPLA2 measuring Calcium ionophore A-23,187-induced arachidonic acid release from bovine platelets with HPLC/UV detection.More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human platelet cPLA2-alpha assessed as arachidonic acid release by vesicle assayMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Concentration required to inhibit human Cytosolic phospholipase A2More data for this Ligand-Target Pair
TargetCytosolic phospholipase A2 beta(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human MGLMore data for this Ligand-Target Pair
Affinity DataEC50: 2.51E+4nMAssay Description:Displacement of [35S]GTP-gamma-S from rat cerebellar CB1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of cPLA2 from human platelets by RP-HPLCMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University Of M£Nster
Curated by ChEMBL
University Of M£Nster
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of FAAH from rat brain microsomes by RP-HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of fatty acid amide hydrolase; range = .23-3 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human platelet cPLA2-alpha activityMore data for this Ligand-Target Pair
Affinity DataIC50: 12.3nMAssay Description:Inhibition of human recombinant FAAH-maltose binding proteinMore data for this Ligand-Target Pair
Affinity DataIC50: 6.46E+3nMAssay Description:Inhibition of human MGL activity using [3H]2-oleoylglycerol substrate by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 12.3nMAssay Description:Inhibition of human FAAHMore data for this Ligand-Target Pair