BDBM50061226 CHEMBL3393714

SMILES Cn1cncc1-c1ccc2[nH]nc(-c3cncc(O[C@H]4CNCCC45CC5)n3)c2c1

InChI Key InChIKey=RQILRUHUVGWBAL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061226   

TargetSerine/threonine-protein kinase pim-1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50061226BDBM50061226(CHEMBL3393714)
Affinity DataIC50: 15nMAssay Description:Inhibition of full length recombinant Pim-1 (unknown origin) assessed as phosphorylation of biotinylated-BAD peptide at Serine 112 residueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50061226BDBM50061226(CHEMBL3393714)
Affinity DataIC50: 58nMAssay Description:Inhibition of full length recombinant Pim-2 (unknown origin) assessed as phosphorylation of biotinylated-BAD peptide at Serine 112 residueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed