BDBM50063396 1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-methyl-2-phenyl-propan-1-one::CHEMBL368752

SMILES CC(C)(C(=O)N1CCN(CC1)C1c2ccc(Cl)cc2CCc2cccnc12)c1ccccc1

InChI Key InChIKey=ZNGBFAOFMLQVNQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50063396   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50063396(1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohept...)
Affinity DataIC50: 3.30E+3nMAssay Description:In vitro inhibition of farnesyltransferase farnesylation of the H-ras oncogeneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed