BDBM50063549 1-(2-Amino-3,3-diphenyl-propionyl)-pyrrolidine-2-carboxylic acid 2,5-dimethyl-benzylamide::CHEMBL269558

SMILES Cc1ccc(C)c(CNC(=O)C2CCCN2C(=O)C(N)C(c2ccccc2)c2ccccc2)c1

InChI Key InChIKey=CCNUHRBZPSRBGO-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50063549   

TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063549(1-(2-Amino-3,3-diphenyl-propionyl)-pyrrolidine-2-c...)
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50063549(1-(2-Amino-3,3-diphenyl-propionyl)-pyrrolidine-2-c...)
Affinity DataKi:  40nMAssay Description:Binding affinity towards thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed