BDBM50063783 1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-hex-5-yn-1-one::1-(3,5-di-tert-butyl-4-hydroxyphenyl)hex-5-yn-1-one::CHEMBL13878::TEBUFELONE
SMILES CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(=O)CCCC#C
InChI Key InChIKey=ZHXUEUKVDMWSKV-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50063783
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Concentration (in microM) to inhibit 50% of Prostaglandin G/H synthase 1 (COX-1) and is expressed in IC50.More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 5-Lipoxygenase(5-LOX)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Concentration (in microM) to inhibit 50% of Prostaglandin G/H synthase 2 (COX-2) and is expressed in IC50.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:The compound was tested for the concentration (in microM) to inhibit 50% of 5-Lipoxygenase (5-LOX) and is expressed in IC50.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 1-lipoxygenase (LOX)in RBL cellsMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair