BDBM50065281 4-[2-Oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-benzoic acid::CHEMBL313259

SMILES: OC(=O)c1ccc(\C=C2/C(=O)Nc3ccccc23)cc1

InChI Key: InChIKey=YILTUWKDVMACDH-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50065281   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM50065281 (4-[2-Oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-ben...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin-like growth factor 1 receptor (Human)	BDBM50065281 (4-[2-Oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-ben...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 1 (Mouse)	BDBM50065281 (4-[2-Oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-ben...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM50065281 (4-[2-Oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-ben...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50065281 (4-[2-Oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-ben...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair