BDBM50065611 CHEMBL3401383
SMILES CCC(CC)CC1(O)CCN(CC1)C(=O)Nc1cc(Oc2ccc(F)cc2)cc(Oc2ccc(cc2)C(N)=O)c1
InChI Key InChIKey=XWGOCGLJLLJAOE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50065611
Affinity DataIC50: 39nMAssay Description:Antagonist activity at human S1P2 receptor overexpressed in CHO cells assessed as increase in intracellular calcium ion concentration incubated 3 min...More data for this Ligand-Target Pair
Affinity DataIC50: >800nMAssay Description:Antagonist activity at human LPA1 receptor overexpressed in CHO cells assessed as increase in intracellular calcium ion concentration after 3 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: >800nMAssay Description:Antagonist activity at human S1P3 receptor overexpressed in CHO cells assessed as increase in intracellular calcium ion concentration after 3 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: >800nMAssay Description:Antagonist activity at human LPA2 receptor overexpressed in CHO cells assessed as increase in intracellular calcium ion concentration after 3 mins by...More data for this Ligand-Target Pair
Affinity DataKd: 198nMAssay Description:Binding affinity to S1PR2 (unknown origin) assessed as dissociation constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Antagonist activity at human S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Displacement of [33P]S1P from human S1P2 expressed in CHO-K1 cells by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at rat S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Displacement of [33P]-S1P from human S1P2 receptor expressed in CHOK1 cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair