BDBM50066334 (S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidine-2-carboxylic acid 5-chloro-2-ethylcarbamoylmethoxy-benzylamide::(S)-1-(2-Amino-2-cyclohexyl-acetyl)-pyrrolidine-2-carboxylic acid 5-chloro-2-ethylcarbamoylmethoxy-benzylamide::1-[2-AMINO-2-CYCLOHEXYL-ACETYL]-PYRROLIDINE-3-CARBOXYLIC ACID 5-CHLORO-2-(2-ETHYLCARBAMOYL-ETHOXY)-BENZYLAMIDE::CHEMBL42039

SMILES CCNC(=O)COc1ccc(Cl)cc1CNC(=O)[C@@H]1CCCN1C(=O)[C@H](N)C1CCCCC1

InChI Key InChIKey=BMHVHOJXEQTIEA-SIKLNZKXSA-N

Data  5 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50066334   

TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066334((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...)
Affinity DataKi:  0.740nMAssay Description:Binding affinity of the compound was evaluated on serine protease thrombin.More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066334((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...)
Affinity DataKi:  0.740nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066334((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...)
Affinity DataKi:  2.30E+4nMAssay Description:Binding affinity of the compound was evaluated on serine protease trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066334((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...)
Affinity DataKi:  2.30E+4nMAssay Description:Inhibition of trypsin in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066334((S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidin...)
Affinity DataKi:  7.10E+4nMAssay Description:Binding affinity of the compound was evaluated on serine protease ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed