BDBM50066565 7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-carboxylic acid cyclopropylamide::CHEMBL119170

SMILES CC(C)(C)c1cc(cc2c1OCC2(C)C)C(=O)NC1CC1

InChI Key InChIKey=DARUDEIEANYQOK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50066565   

TargetProstaglandin G/H synthase 1(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066565(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5...)
Affinity DataIC50: 290nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066565(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5...)
Affinity DataIC50: 550nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066565(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-Lipoxygenase (5-LOX)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed