BDBM50066618 4-{6-[4-amino(imino)methylphenoxy]-2-pyridyloxy}phenyl-iminomethanamine::CHEMBL298415

SMILES NC(=N)c1ccc(Oc2cccc(Oc3ccc(cc3)C(N)=N)n2)cc1

InChI Key InChIKey=VATCDKFGSBVBMX-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50066618   

TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066618(4-{6-[4-amino(imino)methylphenoxy]-2-pyridyloxy}ph...)
Affinity DataKi:  400nMAssay Description:Compound was tested for inhibition activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066618(4-{6-[4-amino(imino)methylphenoxy]-2-pyridyloxy}ph...)
Affinity DataKi:  400nMAssay Description:Inhibition of factor 10a (unknown origin) using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066618(4-{6-[4-amino(imino)methylphenoxy]-2-pyridyloxy}ph...)
Affinity DataKi:  400nMAssay Description:Inhibitory potency was measured against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066618(4-{6-[4-amino(imino)methylphenoxy]-2-pyridyloxy}ph...)
Affinity DataKi:  550nMAssay Description:Inhibitory potency was measured against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066618(4-{6-[4-amino(imino)methylphenoxy]-2-pyridyloxy}ph...)
Affinity DataKi:  550nMAssay Description:Compound was tested for inhibition activity against human thrombin (FIIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066618(4-{6-[4-amino(imino)methylphenoxy]-2-pyridyloxy}ph...)
Affinity DataKi:  600nMAssay Description:Inhibition of thrombin (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066618(4-{6-[4-amino(imino)methylphenoxy]-2-pyridyloxy}ph...)
Affinity DataKi:  2.80E+3nMAssay Description:Inhibitory potency was measured against bovine trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50066618(4-{6-[4-amino(imino)methylphenoxy]-2-pyridyloxy}ph...)
Affinity DataKi:  2.80E+3nMAssay Description:Compound was tested for inhibition activity against bovine trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50066618(4-{6-[4-amino(imino)methylphenoxy]-2-pyridyloxy}ph...)
Affinity DataKi:  9.60E+3nMAssay Description:Inhibition of matriptase-SP1 (615 to 855) (unknown origin) expressed in Escherichia coli BL21(DE3) using Boc-Gln-Ala-Arg-7-amido-4-methyl coumarin hy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed