BDBM50071693 CHEMBL38927::CVS-1578::N-((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2-((S)-2-oxo-3-phenylmethanesulfonylamino-piperidin-1-yl)-acetamide::N-(1-Carbamimidoyl-2-hydroxy-piperidin-3-yl)-2-(2-oxo-3-phenylmethanesulfonylamino-piperidin-1-yl)-acetamide
SMILES NC(=N)N1CCC[C@H](NC(=O)CN2CCC[C@H](NS(=O)(=O)Cc3ccccc3)C2=O)C1O
InChI Key InChIKey=SPUAEQJRVQHWKF-NRAVZPKASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50071693
Affinity DataKi: 1nMAssay Description:Evaluation of inhibition of transition state thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human Tissue type plasminogen activator was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibitory activity was evaluated against thrombolytic enzyme plasminMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:In vitro inhibitory activity was evaluated against thrombin (FIIa)More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibitory activity of the compound was evaluated against Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataIC50: 1.27E+3nMAssay Description:In vitro inhibitory activity of the compound was evaluated against human trypsinMore data for this Ligand-Target Pair
Affinity DataIC50: 791nMAssay Description:Compound was evaluated in vitro for the inhibitory concentration required to inhibit human serine protease enzyme human trypsin by 50%More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+3nMAssay Description:Compound was evaluated in vitro for the inhibitory concentration required to inhibit Coagulation factor X by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Compound was evaluated in vitro for the inhibitory concentration required to inhibit human serine protease enzyme thrombin (FIIa) by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor IIMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataIC50: 1.27E+3nMAssay Description:The compound was tested in vitro for inhibitory activity against human trypsinMore data for this Ligand-Target Pair
Affinity DataIC50: 791nMAssay Description:Inhibitory concentration of the compound required to inhibit human trypsin enzyme was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human plasmin enzyme was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Inhibitory concentration of the compound required to inhibit human thrombin enzyme was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory concentration of the compound required to inhibit human factor Xa enzyme was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 791nMAssay Description:In vitro inhibitory activity was evaluated against human trypsin cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory activity was evaluated against thrombin factor Xa (FXa)More data for this Ligand-Target Pair