BDBM50077576 Benzyl-[2-(1H-indol-4-yloxy)-ethyl]-amine::CHEMBL64283

SMILES C(COc1cccc2[nH]ccc12)NCc1ccccc1

InChI Key InChIKey=ZEHDEZWEFBOGNZ-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50077576   

TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077576(Benzyl-[2-(1H-indol-4-yloxy)-ethyl]-amine | CHEMBL...)
Affinity DataKi:  9.70nMAssay Description:Inhibition of [3H]quinpirole binding to rat striatal membrane Dopamine receptor D2 without GTP and sodiumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077576(Benzyl-[2-(1H-indol-4-yloxy)-ethyl]-amine | CHEMBL...)
Affinity DataKi:  9.70nMAssay Description:In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]quinpirole radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077576(Benzyl-[2-(1H-indol-4-yloxy)-ethyl]-amine | CHEMBL...)
Affinity DataKi:  18nMAssay Description:The compound was tested for binding affinity on [3H]8-OH-DPAT as specific ligand on 5-hydroxytryptamine 1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077576(Benzyl-[2-(1H-indol-4-yloxy)-ethyl]-amine | CHEMBL...)
Affinity DataKi:  20nMAssay Description:Inhibition of [3H]spiperone binding to human Dopamine receptor D3 in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077576(Benzyl-[2-(1H-indol-4-yloxy)-ethyl]-amine | CHEMBL...)
Affinity DataKi:  39nMAssay Description:Inhibition of [3H]quinpirole binding to rat striatal membrane Dopamine receptor D2 without GTP and sodiumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077576(Benzyl-[2-(1H-indol-4-yloxy)-ethyl]-amine | CHEMBL...)
Affinity DataKi:  39nMAssay Description:In vitro low binding affinity towards Dopamine receptor D2 by the displacement of [3H]spiperone radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077576(Benzyl-[2-(1H-indol-4-yloxy)-ethyl]-amine | CHEMBL...)
Affinity DataKi:  82nMAssay Description:Inhibition of [3H]spiperone binding to human Dopamine receptor D2 in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077576(Benzyl-[2-(1H-indol-4-yloxy)-ethyl]-amine | CHEMBL...)
Affinity DataKi:  230nMAssay Description:Inhibition of [3H]spiperone binding to human Dopamine receptor D4.4 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed