BDBM50077588 CHEMBL59737::[2-(1H-Indol-4-yloxy)-ethyl]-(4-phenyl-butyl)-amine

SMILES C(CCc1ccccc1)CNCCOc1cccc2[nH]ccc12

InChI Key InChIKey=XLIMGWVIUMZMMX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077588   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077588(CHEMBL59737 | [2-(1H-Indol-4-yloxy)-ethyl]-(4-phen...)
Affinity DataKi:  0.400nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT radioligand in rat hippocampal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077588(CHEMBL59737 | [2-(1H-Indol-4-yloxy)-ethyl]-(4-phen...)
Affinity DataKi:  5.30nMAssay Description:In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077588(CHEMBL59737 | [2-(1H-Indol-4-yloxy)-ethyl]-(4-phen...)
Affinity DataKi:  14nMAssay Description:In vitro low binding affinity towards Dopamine receptor D2 by the displacement of [3H]-spiperone radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed