BDBM50079043 4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid diamide::4-amino-5,6-dichlorobenzene-1,3-disulfonamide::BDBM50222601::CHEMBL269628

SMILES Nc1c(Cl)c(Cl)c(cc1S(N)(=O)=O)S(N)(=O)=O

InChI Key InChIKey=DNBXGTICJYDFDT-UHFFFAOYSA-N

Data  27 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 50079043   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  0.0360nMAssay Description:Inhibition of human CA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  28nMAssay Description:Inhibitory activity against human recombinant carbonic anhydrase II (CA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  28nMAssay Description:Inhibitory activity against Human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  28nMAssay Description:Inhibitory activity against human recombinant carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  28nMAssay Description:Inhibition of cloned isozyme, human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  28nMAssay Description:Inhibition of human carbonic anhydrase II (CAII)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  28nMAssay Description:Inhibition of human carbonic anhydrase II (hCA II)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  28nMAssay Description:Inhibitory activity against human carbonic anhydrase II (CA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  63nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  174nMAssay Description:Inhibition of bovine carbonic anhydrase IV (CAIV)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  174nMAssay Description:Inhibition of bovine CA4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  175nMAssay Description:Inhibition of bovine carbonic anhydrase IV from bovine lung microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  175nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), isolated from bovine lung microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  175nMAssay Description:Inhibitory activity against bovine lung microsomes carbonic anhydrase isozyme IV (bCA IV).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  175nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), isolated from bovine lung microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  175nMAssay Description:Inhibition of cloned isozyme, human carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  175nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  5.80E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  6.10E+3nMAssay Description:Inhibitory activity against Human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  6.10E+3nMAssay Description:Inhibitory activity against human cloned carbonic anhydrase isozyme I (hCA I, cytosolic form).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  6.10E+3nMAssay Description:Inhibition of cloned isozyme, human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  6.10E+3nMAssay Description:Inhibition of human carbonic anhydrase I (CAI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  6.10E+3nMAssay Description:Inhibitory activity against human recombinant carbonic anhydrase I (CA1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  6.10E+3nMAssay Description:Inhibition of human carbonic anhydrase I (CAI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  6.10E+3nMAssay Description:Inhibitory activity against human carbonic anhydrase I (CA1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  6.10E+3nMAssay Description:Inhibition of human CA1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079043(4-Amino-5,6-dichloro-benzene-1,3-disulfonic acid d...)
Affinity DataKi:  3.57E+7nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed