BDBM50082420 1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-phenyl-propyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-urea::1-(3-chlorophenyl)-3-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)urea::CHEMBL342906

SMILES Clc1cccc(NC(=O)Nc2nc3nn(CCCc4ccccc4)cc3c3nc(nn23)-c2ccco2)c1

InChI Key InChIKey=NVIPLOWTLXCBSA-UHFFFAOYSA-N

Data  14 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50082420   

TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50082420(1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-phenyl-pr...)
Affinity DataKi:  42.6nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50082420(1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-phenyl-pr...)
Affinity DataKi:  43nMAssay Description:Displacement of [125]AB-MECA from human Adenosine A3 receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50082420(1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-phenyl-pr...)
Affinity DataKi:  60nMAssay Description:Binding affinity for human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50082420(1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-phenyl-pr...)
Affinity DataKi:  60nMAssay Description:Antagonist activity at human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50082420(1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-phenyl-pr...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]-MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells; range 51-70More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50082420(1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-phenyl-pr...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50082420(1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-phenyl-pr...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]-SCH- 58261 from human adenosine A2A receptor expressed in CHO cells; range 185-210More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50082420(1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-phenyl-pr...)
Affinity DataKi:  202nMAssay Description:Displacement of specific [3H]-SCH- 58261 binding at human Adenosine A2A receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50082420(1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-phenyl-pr...)
Affinity DataKi:  226nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A2b receptor expressed in CHO cells; range 183-278More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50082420(1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-phenyl-pr...)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [3H]-DPCPX from human Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50082420(1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-phenyl-pr...)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cells; range 1325-1693More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50082420(1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-phenyl-pr...)
Affinity DataKi:  3.20E+3nMAssay Description:Displacement of [3H]-SCH- 58261 from Adenosine A2A receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50082420(1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-phenyl-pr...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50082420(1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-phenyl-pr...)
Affinity DataKi:  6.03E+4nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed