BDBM50083046 5-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-isoxazole-3-carboxylic acid::CHEMBL344122

SMILES Cc1cc2c(cc1-c1cc(no1)C(O)=O)C(C)(C)CCC2(C)C

InChI Key InChIKey=SOHWQOITYAGDRG-UHFFFAOYSA-N

Data  5 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50083046   

TargetRetinoic acid receptor gamma(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50083046(5-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...)
Affinity DataEC50: >1.00E+3nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor beta(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50083046(5-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...)
Affinity DataEC50: >1.00E+3nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor beta(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50083046(5-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...)
Affinity DataKd: >3.00E+3nMAssay Description:In vitro binding affinity for Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50083046(5-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...)
Affinity DataKd: >3.00E+3nMAssay Description:In vitro binding affinity for Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50083046(5-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...)
Affinity DataKd:  5.50E+3nMAssay Description:In vitro binding affinity for Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-gamma(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50083046(5-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...)
Affinity DataKd:  8.10E+3nMAssay Description:In vitro binding affinity for Retinoid X receptor RXR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor alpha(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50083046(5-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphth...)
Affinity DataKd:  9.00E+3nMAssay Description:In vitro binding affinity for Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed