BDBM50083641 Aminopyrimidine (Scaffold II)::CHEMBL113185::N*1*-{5-[2-(3,4,5-Trimethoxy-phenylamino)-pyrimidin-4-yl]-pyridin-2-yl}-ethane-1,2-diamine

SMILES: COc1cc(Nc2nccc(n2)-c2ccc(NCCN)nc2)cc(OC)c1OC

InChI Key: InChIKey=QNULKTUETCUJKC-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50083641   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase TBK1 (Human)	BDBM50083641 (N*1*-{5-[2-(3,4,5-Trimethoxy-phenylamino)-pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ZAP-70 (Human)	BDBM50083641 (N*1*-{5-[2-(3,4,5-Trimethoxy-phenylamino)-pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase CSK (Human)	BDBM50083641 (N*1*-{5-[2-(3,4,5-Trimethoxy-phenylamino)-pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50083641 (N*1*-{5-[2-(3,4,5-Trimethoxy-phenylamino)-pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50083641 (N*1*-{5-[2-(3,4,5-Trimethoxy-phenylamino)-pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Human)	BDBM50083641 (N*1*-{5-[2-(3,4,5-Trimethoxy-phenylamino)-pyrimidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
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