BDBM50085251 1-[2-(Biphenyl-4-yloxy)-ethyl]-pyrrolidine::1-[2-(Biphenyl-4-yloxy)-ethyl]-pyrrolidine(A-78773)::A-78773::CHEMBL119054::SC-22716

SMILES C(CN1CCCC1)Oc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=PKUGRVAJRGZDJP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50085251   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50085251(1-[2-(Biphenyl-4-yloxy)-ethyl]-pyrrolidine | 1-[2-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human leukotriene A4 hydrolase (LTA-4).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50085251(1-[2-(Biphenyl-4-yloxy)-ethyl]-pyrrolidine | 1-[2-...)
Affinity DataIC50:  790nMAssay Description:Inhibition of human whole blood LTB-4 production (Leukotriene B-4).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50085251(1-[2-(Biphenyl-4-yloxy)-ethyl]-pyrrolidine | 1-[2-...)
Affinity DataIC50:  790nMAssay Description:Inhibitory activity was determined for LTB4 production in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50085251(1-[2-(Biphenyl-4-yloxy)-ethyl]-pyrrolidine | 1-[2-...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity was determined against Leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed