BDBM50085331 (4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine::4-ethynyl-N,N-dipropylcyclohex-3-enamine::CHEMBL162762

SMILES CCCN(CCC)C1CCC(=CC1)C#C

InChI Key InChIKey=IOUKEEFTYOZOKJ-UHFFFAOYSA-N

Data  27 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 29 hits for monomerid = 50085331   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  5.20nMAssay Description:Binding Affinity was tested on the high affinity site of Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  15nMAssay Description:Binding Affinity was tested on high Affinity Site of Bovine dopamine receptor D2. Tested for ability to displace the radioligand [3H]pramipexoleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  22nMAssay Description:Binding Affinity was tested on the high affinity site of Dopamine receptor D4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  23nMAssay Description:Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  34nMAssay Description:Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D2SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  38nMAssay Description:Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D2LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  38nMAssay Description:Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  40nMAssay Description:Binding Affinity was tested on relative proportion of high Affinity Site of Bovine dopamine receptor D2. Tested for ability to displace the radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  57nMAssay Description:Binding Affinity was tested on high Affinity Site of Bovine Dopamine D2 Receptor. Tested for ability to displace the radioligand [3H]-SpiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  170nMAssay Description:Dissociation constant of compound on one-site model Dopamine receptor D4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]spiperone from human wild type D3 receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  250nMAssay Description:Binding Affinity on High Affinity Site of Dopamine receptor D2SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  270nMAssay Description:Binding affinity on High Affinity Site of Dopamine receptor D2LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  350nMAssay Description:Dissociation constant of compound on one-site model Human Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  380nMAssay Description:Binding Affinity was tested on low Affinity Site of Dopamine receptor D4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  590nMAssay Description:Binding Affinity was tested on low Affinity Site of Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  720nMAssay Description:Binding Affinity was determined in the presence of 100 micro M Gpp(NH)p for decoupling of the ternary complex of Compound to Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  750nMAssay Description:Dissociation constant of compound on one-site model Bovine dopamine receptor D2. Tested for ability to displace the radioligand [3H]spiperone at the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  2.80E+3nMAssay Description:Dissociation constant of compound on one-site model Dopamine receptor D2LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  2.90E+3nMAssay Description:Dissociation constant of compound on one-site model Dopamine receptor D2SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  4.10E+3nMAssay Description:Binding Affinity was tested on low Affinity Site of Bovine dopamine receptor D2. Tested for ability to displace the radioligand [3H]spiperone at the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  1.20E+4nMAssay Description:Binding Affinity of Compound of Dopamine receptor D2SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  1.40E+4nMAssay Description:Binding Affinity was tested on low Affinity Site of Dopamine receptor D2LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  1.70E+4nMAssay Description:Binding Affinity was determined for decoupling of the ternary complex of Compound to Bovine dopamine receptor D1. Tested for ability to displace the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  1.70E+4nMAssay Description:Binding Affinity was determined in the presence of 100 micro M Gpp(NH)p for decoupling of the ternary complex of Compound to Dopamine receptor D2SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi:  1.90E+4nMAssay Description:Binding Affinity was determined in the presence of 100 micro M Gpp(NH)p for decoupling of the ternary complex of Compound to Dopamine receptor D2LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataKi: >2.00E+4nMAssay Description:Binding Affinity was tested on High Affinity Site of Bovine dopamine receptor D1. Tested for ability to displace the radioligand [3H]-SCH- 23390More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataEC50:  7.70nMAssay Description:Intrinsic activity at human D3 receptor expressed in CHO dhfr- cells assessed as inhibition of forskolin-induced cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50085331((4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine | 4-eth...)
Affinity DataEC50:  4.40nMAssay Description:Intrinsic activity at human D3 receptor expressed in CHO dhfr- cells by [3H]thymidine incorporation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed