BDBM50085363 CHEMBL60718::L-1-Tosylamido-2-phenylethyl chloromethyl ketone::N-Tosyl-L-phenylalanine chloromethyl ketone::N-Tosyl-L-phenylalanyl chloromethyl ketone::N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]-4-methylbenzenesulfonamide::TPCK::Tos-Phe-CH2Cl::Tosylphenylalanyl chloromethyl ketone::cid_439647::l-N-(alpha-(Chloroacetyl)phenethyl)-p-toluenesulfonamide

SMILES Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc1ccccc1)C(=O)CCl

InChI Key InChIKey=MQUQNUAYKLCRME-INIZCTEOSA-N

Data  8 IC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50085363   

TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50085363(CHEMBL60718 | L-1-Tosylamido-2-phenylethyl chlorom...)
Affinity DataIC50:  1.30E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPerilipin-1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50085363(CHEMBL60718 | L-1-Tosylamido-2-phenylethyl chlorom...)
Affinity DataIC50:  1.87E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPerilipin-5(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50085363(CHEMBL60718 | L-1-Tosylamido-2-phenylethyl chlorom...)
Affinity DataIC50:  1.90E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTrypsin(Sus scrofa)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085363(CHEMBL60718 | L-1-Tosylamido-2-phenylethyl chlorom...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibitory activity against porcine pancreatic trypsin (TRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085363(CHEMBL60718 | L-1-Tosylamido-2-phenylethyl chlorom...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibitory activity against human leukocyte cathepsin GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085363(CHEMBL60718 | L-1-Tosylamido-2-phenylethyl chlorom...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibitory activity against human serine protease chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085363(CHEMBL60718 | L-1-Tosylamido-2-phenylethyl chlorom...)
Affinity DataIC50:  1.40E+5nMAssay Description:Inhibitory activity against alpha-chymotrypsin(alpha-CT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50085363(CHEMBL60718 | L-1-Tosylamido-2-phenylethyl chlorom...)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibitory activity against porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed