BDBM50085402 4-{4-[3-(5-Carbamimidoyl-2-hydroxy-phenyl)-allylcarbamoyl]-phenyl}-pyridine-2-carboxylic acid amide::CHEMBL67692

SMILES NC(=N)c1ccc(O)c(\C=C\CNC(=O)c2ccc(cc2)-c2ccnc(c2)C(N)=O)c1

InChI Key InChIKey=VSHBEBIVNLJTGI-OWOJBTEDSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50085402   

TargetCoagulation factor X(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085402(4-{4-[3-(5-Carbamimidoyl-2-hydroxy-phenyl)-allylca...)
Affinity DataKi:  0.75nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085402(4-{4-[3-(5-Carbamimidoyl-2-hydroxy-phenyl)-allylca...)
Affinity DataKi:  2.20E+3nMAssay Description:In vitro inhibition of trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085402(4-{4-[3-(5-Carbamimidoyl-2-hydroxy-phenyl)-allylca...)
Affinity DataKi: >4.00E+3nMAssay Description:In vitro inhibition of coagulation factor IIa.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085402(4-{4-[3-(5-Carbamimidoyl-2-hydroxy-phenyl)-allylca...)
Affinity DataKi: >7.30E+3nMAssay Description:Compound was tested for its inhibitory activity against PlasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085402(4-{4-[3-(5-Carbamimidoyl-2-hydroxy-phenyl)-allylca...)
Affinity DataKi:  7.70E+3nMAssay Description:Compound was tested for its inhibitory activity against tissue plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed