BDBM50088118 2-(N-(4-nitrobenzyl)-2,3,4,5,6-pentafluorophenylsulfonamido)-N-hydroxyacetamide::CHEMBL293503::N-Hydroxy-2-[(4-nitro-benzyl)-pentafluorobenzenesulfonyl-amino]-acetamide

SMILES ONC(=O)CN(Cc1ccc(cc1)[N+]([O-])=O)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F

InChI Key InChIKey=GWQRQVFEMGHPMD-UHFFFAOYSA-N

Data  8 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50088118   

TargetNeutrophil collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088118(2-(N-(4-nitrobenzyl)-2,3,4,5,6-pentafluorophenylsu...)
Affinity DataKi:  0.100nMAssay Description:Inhibitory activity against the Matrix Metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088118(2-(N-(4-nitrobenzyl)-2,3,4,5,6-pentafluorophenylsu...)
Affinity DataKi:  0.600nMAssay Description:Inhibitory activity against the Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088118(2-(N-(4-nitrobenzyl)-2,3,4,5,6-pentafluorophenylsu...)
Affinity DataKi:  0.603nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50088118(2-(N-(4-nitrobenzyl)-2,3,4,5,6-pentafluorophenylsu...)
Affinity DataKi:  0.692nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50088118(2-(N-(4-nitrobenzyl)-2,3,4,5,6-pentafluorophenylsu...)
Affinity DataKi:  0.700nMAssay Description:Inhibitory activity against the Matrix Metalloprotease 2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088118(2-(N-(4-nitrobenzyl)-2,3,4,5,6-pentafluorophenylsu...)
Affinity DataKi:  3nMAssay Description:Inhibitory activity against the Matrix Metalloprotease 1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50088118(2-(N-(4-nitrobenzyl)-2,3,4,5,6-pentafluorophenylsu...)
Affinity DataKi:  5nMAssay Description:Inhibitory activity against the Clostridium histolyticum collagenase (ChC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088118(2-(N-(4-nitrobenzyl)-2,3,4,5,6-pentafluorophenylsu...)
Affinity DataKi:  5nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50088118(2-(N-(4-nitrobenzyl)-2,3,4,5,6-pentafluorophenylsu...)
Affinity DataIC50:  3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed