BDBM50088906 (5,7-Diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-methyl-amine::CHEMBL366831::N-methyl-5,7-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

SMILES CNc1ncnc2n(cc(-c3ccccc3)c12)-c1ccccc1

InChI Key InChIKey=XUCUUSDIHUJLCZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50088906   

TargetTyrosine-protein kinase ABL1/ABL2(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50088906(N-methyl-5,7-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Tested in vitro for inhibition of non-receptor tyrosine kinase v-AblMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Chicken)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50088906(N-methyl-5,7-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Tested for inhibition of protein tyrosine kinase c-Src phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50088906(N-methyl-5,7-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50088906(N-methyl-5,7-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Tested in vitro for inhibition of serine/threonine kinase Cdc2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50088906(N-methyl-5,7-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4...)
Affinity DataIC50: 3.10E+4nMAssay Description:Tested for inhibition of EGF-receptor tyrosine kinase in intact cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed